Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes


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Ratio description Regulation Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio
Results: HTML CSV LaTeX Showing element 501 to 550 of 1166 in total
Regulation	down
Ratio description Class Gene Ontology 1.48389 Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Source:Uniprot/SWISSPROT;Acc:P49790] cellular component intracellular 1.48389 Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Source:Uniprot/SWISSPROT;Acc:P49790] cellular component nuclear pore 1.48389 Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Source:Uniprot/SWISSPROT;Acc:P49790] cellular component nucleus 1.48389 Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Source:Uniprot/SWISSPROT;Acc:P49790] cellular component proton-transporting two-sector ATPase complex 1.48389 Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Source:Uniprot/SWISSPROT;Acc:P49790] molecular function ATP binding 1.48389 Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Source:Uniprot/SWISSPROT;Acc:P49790] molecular function DNA binding 1.48389 Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Source:Uniprot/SWISSPROT;Acc:P49790] molecular function hydrogen ion transporting ATP synthase activity, rotational mechanism 1.48389 Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Source:Uniprot/SWISSPROT;Acc:P49790] molecular function hydrogen ion transporting ATPase activity, rotational mechanism 1.48389 Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Source:Uniprot/SWISSPROT;Acc:P49790] molecular function metal ion binding 1.48389 Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Source:Uniprot/SWISSPROT;Acc:P49790] molecular function protein binding 1.48389 Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Source:Uniprot/SWISSPROT;Acc:P49790] molecular function transporter activity 1.48389 Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Source:Uniprot/SWISSPROT;Acc:P49790] molecular function zinc ion binding 1.49271 Cullin-4B (CUL-4B). [Source:Uniprot/SWISSPROT;Acc:Q13620] biological process cell cycle 1.49271 Cullin-4B (CUL-4B). [Source:Uniprot/SWISSPROT;Acc:Q13620] biological process DNA repair 1.49271 Cullin-4B (CUL-4B). [Source:Uniprot/SWISSPROT;Acc:Q13620] biological process ubiquitin cycle 1.49271 Cullin-4B (CUL-4B). [Source:Uniprot/SWISSPROT;Acc:Q13620] cellular component cellular_component 1.49271 Cullin-4B (CUL-4B). [Source:Uniprot/SWISSPROT;Acc:Q13620] molecular function molecular_function 1.49271 Cullin-4B (CUL-4B). [Source:Uniprot/SWISSPROT;Acc:Q13620] molecular function protein binding 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process BMP signaling pathway 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process bone mineralization 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process cardiac cell differentiation 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process cartilage development 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process cell fate commitment 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process cell growth 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process cell-cell signaling 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process embryonic development 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process epithelial to mesenchymal transition 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process growth 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process inflammatory response 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process negative regulation of cell proliferation 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process negative regulation of progression through cell cycle 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process odontogenesis (sensu Vertebrata) 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process organ morphogenesis 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process osteoblast differentiation 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process positive regulation of astrocyte differentiation 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process positive regulation of ossification 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process positive regulation of osteoblast differentiation 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process regulation of transcription 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] biological process ureteric bud branching 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] cellular component extracellular region 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] cellular component extracellular space 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] molecular function cytokine activity 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] molecular function growth factor activity 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] molecular function protein binding 1.49558 Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Source:Uniprot/SWISSPROT;Acc:P12643] molecular function transforming growth factor beta receptor binding 1.49923 Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP). [Source:Uniprot/SWISSPROT;Acc:Q13905] biological process blood vessel development 1.49923 Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP). [Source:Uniprot/SWISSPROT;Acc:Q13905] biological process cell-cell adhesion 1.49923 Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP). [Source:Uniprot/SWISSPROT;Acc:Q13905] biological process platelet-derived growth factor receptor signaling pathway 1.49923 Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP). [Source:Uniprot/SWISSPROT;Acc:Q13905] biological process regulation of small GTPase mediated signal transduction 1.49923 Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP). [Source:Uniprot/SWISSPROT;Acc:Q13905] biological process signal transduction Legend: - The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration. - The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. - The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. - The Gene Ontology terms as linked to the specific gene.

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