Scientific
MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis
These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.
Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio
Results: HTML CSV LaTeX
Showing element 101 to 150 of 2667 in total
Ratio	Regulation	description	Class	Gene Ontology	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	biological process	protein targeting	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	biological process	regulation of neuron differentiation	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	biological process	regulation of signal transduction	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	biological process	regulation of synaptic plasticity	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	cellular component	cytoplasm	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	molecular function	insulin-like growth factor receptor binding	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	molecular function	protein domain specific binding	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	molecular function	protein kinase C binding	
1.14311	down	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1). [Source:Uniprot/SWISSPROT;Acc:P61981]	molecular function	protein kinase C inhibitor activity	
1.14915	up	Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Source:Uniprot/SWISSPROT;Acc:Q13445]	biological process	cell-cell signaling	
1.14915	up	Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Source:Uniprot/SWISSPROT;Acc:Q13445]	biological process	signal transduction	
1.14915	up	Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Source:Uniprot/SWISSPROT;Acc:Q13445]	biological process	transport	
1.14915	up	Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Source:Uniprot/SWISSPROT;Acc:Q13445]	cellular component	integral to membrane	
1.14915	up	Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Source:Uniprot/SWISSPROT;Acc:Q13445]	cellular component	membrane	
1.14915	up	Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Source:Uniprot/SWISSPROT;Acc:Q13445]	molecular function	receptor binding	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	biological process	cell adhesion	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	cellular component	integral to plasma membrane	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	cellular component	membrane	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	cellular component	viral capsid	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	molecular function	glycosaminoglycan binding	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	molecular function	protein binding	
1.15279	up	Podocalyxin-like protein 2 precursor (Endoglycan). [Source:Uniprot/SWISSPROT;Acc:Q9NZ53]	molecular function	structural molecule activity	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	biological process	electron transport	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	biological process	signal transduction	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	cellular component	extracellular region	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	molecular function	electron carrier activity	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	molecular function	enzyme activator activity	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	molecular function	guanylate cyclase activator activity	
1.1611	down	Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. [Source:Uniprot/SWISSPROT;Acc:Q02747]	molecular function	hormone activity	
1.16158	up	transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 [Source:RefSeq_dna;Acc:NR_002720]	biological process	calcium ion transport	
1.16158	up	transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 [Source:RefSeq_dna;Acc:NR_002720]	biological process	ion transport	
1.16158	up	transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 [Source:RefSeq_dna;Acc:NR_002720]	cellular component	membrane	
1.16158	up	transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 [Source:RefSeq_dna;Acc:NR_002720]	molecular function	calcium channel activity	
1.16158	up	transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 [Source:RefSeq_dna;Acc:NR_002720]	molecular function	ion channel activity	
1.16173	up	oligonucleotide/oligosaccharide-binding fold containing 2B [Source:RefSeq_peptide;Acc:NP_076973]	molecular function	nucleic acid binding	
1.16363	up	Sperm acrosome membrane-associated protein 1 precursor (Sperm acrosomal membrane-associated protein 32). [Source:Uniprot/SWISSPROT;Acc:Q9HBV2]	cellular component	integral to membrane	
1.16363	up	Sperm acrosome membrane-associated protein 1 precursor (Sperm acrosomal membrane-associated protein 32). [Source:Uniprot/SWISSPROT;Acc:Q9HBV2]	cellular component	membrane	
1.16393	up	olfactory receptor, family 5, subfamily K, member 4 [Source:RefSeq_peptide;Acc:NP_001005517]	biological process	G-protein coupled receptor protein signaling pathway	
1.16393	up	olfactory receptor, family 5, subfamily K, member 4 [Source:RefSeq_peptide;Acc:NP_001005517]	cellular component	integral to membrane	
1.16393	up	olfactory receptor, family 5, subfamily K, member 4 [Source:RefSeq_peptide;Acc:NP_001005517]	molecular function	olfactory receptor activity	
1.16393	up	olfactory receptor, family 5, subfamily K, member 4 [Source:RefSeq_peptide;Acc:NP_001005517]	molecular function	rhodopsin-like receptor activity	
1.16499	up	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3). [Source:Uniprot/SWISSPROT;Acc:Q9P0K1]	biological process	cell adhesion	
1.16499	up	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3). [Source:Uniprot/SWISSPROT;Acc:Q9P0K1]	biological process	central nervous system development	
1.16499	up	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3). [Source:Uniprot/SWISSPROT;Acc:Q9P0K1]	biological process	negative regulation of cell adhesion	
1.16499	up	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3). [Source:Uniprot/SWISSPROT;Acc:Q9P0K1]	biological process	proteolysis	
1.16499	up	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3). [Source:Uniprot/SWISSPROT;Acc:Q9P0K1]	cellular component	integral to membrane	
1.16499	up	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3). [Source:Uniprot/SWISSPROT;Acc:Q9P0K1]	cellular component	membrane	
1.16499	up	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3). [Source:Uniprot/SWISSPROT;Acc:Q9P0K1]	molecular function	integrin binding	
1.16499	up	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3). [Source:Uniprot/SWISSPROT;Acc:Q9P0K1]	molecular function	metalloendopeptidase activity	
1.16499	up	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3). [Source:Uniprot/SWISSPROT;Acc:Q9P0K1]	molecular function	protein binding	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.
- http://analysis.yellowcouch.org/