Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio Regulation description Class Gene Ontology Gene Minimum Ratio Accession Maximum Ratio

Results: HTML CSV LaTeX

Showing element 701 to 750 of 2667 in total


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\def\wcC{0.16666666666667\textwidth}
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\def\wcE{0.16666666666667\textwidth}
\begin{longtable}{|c|c|c|c|c|}
\hline
\parbox{\wcA}{\vspace{3pt}\noindent
Ratio\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Regulation\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
description\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
Class\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
Gene Ontology\vspace{3pt}}\\
\hline
\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.29238\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
Coiled-coil and C2 domain-containing protein 1B. \vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
oxidoreductase activity\vspace{3pt}}\\\hline
\multirow{3}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.29424\vspace{3pt}}}&\multirow{49}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
down\vspace{3pt}}}&\multirow{3}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Calcyphosin-2 (Calcyphosine-2). \vspace{3pt}}}&\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
ciliary or flagellar motility\vspace{3pt}}\\\cline{4-5}
&&&\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
flagellin-based flagellum\vspace{3pt}}\\\cline{4-5}
&&&\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
calcium ion binding\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{7}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.2984\vspace{3pt}}}&&\multirow{7}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
nucleolar and spindle associated protein 1 isoform 2 \vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
cytokinesis after mitosis\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
establishment of mitotic spindle localization\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
mitotic chromosome condensation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of mitosis\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
nucleolus\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
spindle microtubule\vspace{3pt}}\\\cline{4-5}
&&&\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
microtubule binding\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{3}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.29952\vspace{3pt}}}&&\multirow{3}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Melanoma-associated antigen C2 (MAGE-C2 antigen) (MAGE-E1 antigen) (Hepatocellular carcinoma-associated antigen 587) (Cancer-testis antigen 10) (CT10). \vspace{3pt}}}&\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
regulation of progression through cell cycle\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
cytoplasm\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
nucleus\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{7}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.30082\vspace{3pt}}}&&\multirow{7}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2). \vspace{3pt}}}&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
regulation of global transcription from RNA polymerase II promoter\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
regulation of transcription\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
regulation of transcription, DNA-dependent\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
cytoplasm\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
nucleus\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
RNA polymerase II transcription mediator activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
transcription regulator activity\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{29}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.30142\vspace{3pt}}}&&\multirow{29}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen). \vspace{3pt}}}&\multirow{16}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
cell growth\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
fibroblast growth factor receptor signaling pathway\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
forebrain development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
hair cell differentiation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
inner ear development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
JAK-STAT cascade\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
MAPKKK cascade\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
morphogenesis of an epithelium\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
negative regulation of epithelial cell proliferation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of apoptosis\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of cell differentiation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of peptidyl-tyrosine phosphorylation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of protein ubiquitination\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein amino acid phosphorylation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
sensory perception of sound\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
skeletal development\vspace{3pt}}\\\cline{4-5}
&&&\multirow{6}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
integral to membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
integral to plasma membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
internal side of plasma membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
lysosome\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
perinuclear region of cytoplasm\vspace{3pt}}\\\cline{4-5}
&&&\multirow{7}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
ATP binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
fibroblast growth factor receptor activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
identical protein binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
interleukin-1 receptor activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
nucleotide binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein kinase activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein serine/threonine kinase activity\vspace{3pt}}\\\hline
nd{longtable}

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.

 - The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 

 - The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 

 - The Gene Ontology terms as linked to the specific gene.

 - Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray

 - Accession is the GO accession key. 

 - Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

 - Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

- http://analysis.yellowcouch.org/