MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio	Accession	Gene Ontology	description	Regulation	Class	Minimum Ratio	Gene	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 351 to 400 of 2667 in total

Ratio	Gene Ontology	description	Regulation	Class
1.20619	GABA-B receptor activity	Sodium/potassium-transporting ATPase subunit alpha-4 (EC 3.6.3.9) (Sodium pump subunit alpha-4) (Na(+)/K(+) ATPase alpha-4 subunit). [Uniprot/SWISSPROT;Acc:Q13733]	down	molecular function
	hydrogen ion homeostasis			biological process
	hydrolase activity			molecular function
	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
	integral to membrane			cellular component
	magnesium ion binding			molecular function
	membrane			cellular component
	metabolic process			biological process
	monovalent inorganic cation transport
	monovalent inorganic cation transporter activity			molecular function
	nucleotide binding
	potassium ion binding
	potassium ion transport			biological process
	proton transport
	sodium ion binding			molecular function
	sodium ion transport			biological process
	sodium:potassium-exchanging ATPase activity			molecular function
	sodium:potassium-exchanging ATPase complex			cellular component
	sperm motility			biological process
	transport
1.20924	3-chloroallyl aldehyde dehydrogenase activity	Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3). [Uniprot/SWISSPROT;Acc:P47895]		molecular function
	alcohol metabolic process			biological process
	aldehyde dehydrogenase [NAD(P)+] activity			molecular function
	cytoplasm			cellular component
	embryonic eye morphogenesis			biological process
	lipid metabolic process
	metabolic process
	nucleus accumbens development
	optic cup morphogenesis involved in camera-type eye development
	oxidoreductase activity			molecular function
	positive regulation of apoptosis			biological process
	retinoic acid metabolic process
1.21384	catalytic activity	Disco-interacting protein 2 homolog C. [Uniprot/SWISSPROT;Acc:Q9Y2E4]		molecular function
	metabolic process			biological process
	nucleus			cellular component
	transcription factor binding			molecular function
1.21657	cell cycle	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1). [Uniprot/SWISSPROT;Acc:Q99719]	up	biological process
	cytokinesis
	GTP binding			molecular function
	GTPase activity
	nucleotide binding
	plasma membrane			cellular component
	positive regulation of exocytosis			biological process
	protein binding			molecular function
	regulation of exocytosis			biological process
	small GTPase mediated signal transduction
	structural molecule activity			molecular function
	synaptic vesicle			cellular component
	synaptic vesicle targeting			biological process
	synaptosome			cellular component

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.