Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio Regulation description Gene Ontology Class Gene Accession Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2569 to 2618 of 2667 in total

Ratio	Regulation	description	Gene Ontology	Class	
5.31521	up	Rho-related BTB domain-containing protein 1. [Source:Uniprot/SWISSPROT;Acc:O94844]	small GTPase mediated signal transduction	biological process	
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Source:Uniprot/SWISSPROT;Acc:Q12968]	cellular respiration	biological process	
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Source:Uniprot/SWISSPROT;Acc:Q12968]	cytoplasm	cellular component	
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Source:Uniprot/SWISSPROT;Acc:Q12968]	heart development	biological process	
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Source:Uniprot/SWISSPROT;Acc:Q12968]	inflammatory response	biological process	
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Source:Uniprot/SWISSPROT;Acc:Q12968]	nucleus	cellular component	
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Source:Uniprot/SWISSPROT;Acc:Q12968]	protein binding	molecular function	
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Source:Uniprot/SWISSPROT;Acc:Q12968]	regulation of transcription	biological process	
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Source:Uniprot/SWISSPROT;Acc:Q12968]	regulation of transcription from RNA polymerase II promoter	biological process	
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Source:Uniprot/SWISSPROT;Acc:Q12968]	regulation of transcription, DNA-dependent	biological process	
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Source:Uniprot/SWISSPROT;Acc:Q12968]	transcription coactivator activity	molecular function	
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Source:Uniprot/SWISSPROT;Acc:Q12968]	transcription factor activity	molecular function	
5.53059	up	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	GTP binding	molecular function	
5.53059	up	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	GTPase activity	molecular function	
5.53059	up	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	heat shock protein binding	molecular function	
5.53059	up	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	intracellular	cellular component	
5.53059	up	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	intracellular protein transport	biological process	
5.53059	up	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	nucleocytoplasmic transport	biological process	
5.53059	up	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	nucleotide binding	molecular function	
5.53059	up	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	protein binding	molecular function	
5.53059	up	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	protein transport	biological process	
5.53059	up	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	signal transduction	biological process	
5.53059	up	rab and DnaJ domain containing [Source:RefSeq_peptide;Acc:NP_057628]	small GTPase mediated signal transduction	biological process	
5.61927	down	RING finger protein 170 (Putative LAG1-interacting protein). [Source:Uniprot/SWISSPROT;Acc:Q96K19]	integral to membrane	cellular component	
5.61927	down	RING finger protein 170 (Putative LAG1-interacting protein). [Source:Uniprot/SWISSPROT;Acc:Q96K19]	membrane	cellular component	
5.61927	down	RING finger protein 170 (Putative LAG1-interacting protein). [Source:Uniprot/SWISSPROT;Acc:Q96K19]	metal ion binding	molecular function	
5.61927	down	RING finger protein 170 (Putative LAG1-interacting protein). [Source:Uniprot/SWISSPROT;Acc:Q96K19]	nucleoside transporter activity	molecular function	
5.61927	down	RING finger protein 170 (Putative LAG1-interacting protein). [Source:Uniprot/SWISSPROT;Acc:Q96K19]	protein binding	molecular function	
5.61927	down	RING finger protein 170 (Putative LAG1-interacting protein). [Source:Uniprot/SWISSPROT;Acc:Q96K19]	transport	biological process	
5.61927	down	RING finger protein 170 (Putative LAG1-interacting protein). [Source:Uniprot/SWISSPROT;Acc:Q96K19]	zinc ion binding	molecular function	
5.81102	up	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	cell surface	cellular component	
5.81102	up	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	cytoplasm	cellular component	
5.81102	up	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	cytoskeleton	cellular component	
5.81102	up	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	metal ion binding	molecular function	
5.81102	up	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	nucleus	cellular component	
5.81102	up	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	protein binding	molecular function	
5.81102	up	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein). [Source:Uniprot/SWISSPROT;Acc:Q96JY6]	zinc ion binding	molecular function	
5.83544	down	Nucleoplasmin-2. [Source:Uniprot/SWISSPROT;Acc:Q86SE8]	chromatin remodeling	biological process	
5.83544	down	Nucleoplasmin-2. [Source:Uniprot/SWISSPROT;Acc:Q86SE8]	cytoplasmic chromatin	cellular component	
5.83544	down	Nucleoplasmin-2. [Source:Uniprot/SWISSPROT;Acc:Q86SE8]	embryonic development	biological process	
5.83544	down	Nucleoplasmin-2. [Source:Uniprot/SWISSPROT;Acc:Q86SE8]	histone binding	molecular function	
5.83544	down	Nucleoplasmin-2. [Source:Uniprot/SWISSPROT;Acc:Q86SE8]	nuclear chromatin	cellular component	
5.83544	down	Nucleoplasmin-2. [Source:Uniprot/SWISSPROT;Acc:Q86SE8]	nucleic acid binding	molecular function	
5.83544	down	Nucleoplasmin-2. [Source:Uniprot/SWISSPROT;Acc:Q86SE8]	nucleus	cellular component	
5.83544	down	Nucleoplasmin-2. [Source:Uniprot/SWISSPROT;Acc:Q86SE8]	oocyte differentiation	biological process	
5.83544	down	Nucleoplasmin-2. [Source:Uniprot/SWISSPROT;Acc:Q86SE8]	positive regulation of meiosis	biological process	
5.83544	down	Nucleoplasmin-2. [Source:Uniprot/SWISSPROT;Acc:Q86SE8]	regulation of exit from mitosis	biological process	
5.83544	down	Nucleoplasmin-2. [Source:Uniprot/SWISSPROT;Acc:Q86SE8]	single fertilization	biological process	
5.84607	down	Tubulin-specific chaperone E (Tubulin-folding cofactor E). [Source:Uniprot/SWISSPROT;Acc:Q15813]	axonogenesis	biological process	
5.84607	down	Tubulin-specific chaperone E (Tubulin-folding cofactor E). [Source:Uniprot/SWISSPROT;Acc:Q15813]	beta-tubulin folding	biological process	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.

- http://analysis.yellowcouch.org/