MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio	Regulation	description	Gene Ontology	Class	Accession	Gene	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1551 to 1600 of 2667 in total

Ratio	Regulation	description	Gene Ontology	Class
1.76994	down	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha). [Uniprot/SWISSPROT;Acc:O43184]	cell adhesion	biological process
			integral to membrane	cellular component
			metal ion binding	molecular function
			metalloendopeptidase activity
			metallopeptidase activity
			myoblast fusion	biological process
			plasma membrane	cellular component
			protein binding	molecular function
			proteolysis	biological process
			zinc ion binding	molecular function
1.78439	up	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta). [Uniprot/SWISSPROT;Acc:Q14839]	ATP binding
			ATP-dependent DNA helicase activity
			ATP-dependent helicase activity
			chromatin	cellular component
			chromatin assembly or disassembly	biological process
			chromatin binding	molecular function
			chromatin modification	biological process
			chromosome organization and biogenesis (sensu Eukaryota)
			DNA binding	molecular function
			helicase activity
			hydrolase activity
			intracellular signaling cascade	biological process
			metal ion binding	molecular function
			nucleic acid binding
			nucleotide binding
			nucleus	cellular component
			protein binding	molecular function
			regulation of transcription from RNA polymerase II promoter	biological process
			transcription
			transcription factor binding	molecular function
			zinc ion binding
1.78708		Centromere protein L (CENP-L) (Interphase centromere complex protein 33). [Uniprot/SWISSPROT;Acc:Q8N0S6]	chromosome	cellular component
			chromosome, pericentric region
			nucleus
1.79094		Protein FAM65A. [Uniprot/SWISSPROT;Acc:Q6ZS17]	binding	molecular function
			intracellular	cellular component
			signal transduction	biological process
1.7961		RAS-like, family 11, member A [RefSeq_peptide;Acc:NP_996563]	GTP binding	molecular function
			intracellular	cellular component
			nucleotide binding	molecular function
			protein transport	biological process
			small GTPase mediated signal transduction
1.80858	down	Rhophilin-1 (GTP-Rho-binding protein 1). [Uniprot/SWISSPROT;Acc:Q8TCX5]	intracellular	cellular component
			protein binding	molecular function
			signal transduction	biological process
			small GTPase regulator activity	molecular function
1.80942		Uncharacterized protein C18orf26. [Uniprot/SWISSPROT;Acc:Q8N1N2]	integral to membrane	cellular component
			membrane
1.81557		Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80). [Uniprot/SWISSPROT;Acc:Q9ULG1]	ATP binding	molecular function
			DNA binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.