MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio	Regulation	description	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1301 to 1350 of 2667 in total

Ratio	Regulation	description	Gene Ontology	Class
1.59819	up	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2). [Uniprot/SWISSPROT;Acc:O14830]	calcium ion binding	molecular function
			detection of stimulus during sensory perception	biological process
			hydrolase activity	molecular function
			iron ion binding
			manganese ion binding
			phosphoprotein phosphatase activity
			protein amino acid dephosphorylation	biological process
			protein serine/threonine phosphatase activity	molecular function
			response to stimulus	biological process
			visual perception
1.60668		Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC [Uniprot/SWISSPROT;Acc:Q9HBA0]	calcium channel activity	molecular function
			calcium ion binding
			calcium ion homeostasis	biological process
			calcium ion transport
			calmodulin binding	molecular function
			identical protein binding
			integral to membrane	cellular component
			ion channel activity	molecular function
			ion transport	biological process
			membrane	cellular component
			osmosensory signaling pathway	biological process
			plasma membrane	cellular component
			regulation of cell volume	biological process
			response to mechanical stimulus
1.60746	down	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein). [Uniprot/SWISSPROT;Acc:Q8TD26]	ATP binding	molecular function
			ATP-dependent helicase activity
			chromatin	cellular component
			chromatin assembly or disassembly	biological process
			chromatin binding	molecular function
			chromatin remodeling	biological process
			DNA binding	molecular function
			helicase activity
			hydrolase activity
			integral to membrane	cellular component
			nervous system development	biological process
			nucleic acid binding	molecular function
			nucleosome	cellular component
			nucleosome assembly	biological process
			nucleotide binding	molecular function
			nucleus	cellular component
			regulation of transcription, DNA-dependent	biological process
			response to antibiotic
			tetracycline transport
			tetracycline:hydrogen antiporter activity	molecular function
			transcription	biological process
1.61347		Calmodulin-like protein 5 (Calmodulin-like skin protein). [Uniprot/SWISSPROT;Acc:Q9NZT1]	calcium ion binding	molecular function
			ciliary or flagellar motility	biological process
			epidermis development
			flagellin-based flagellum	cellular component
			protein binding	molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.