MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Regulation	Ratio	Gene Ontology	description	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 118 to 167 of 2667 in total

Regulation  : down

Ratio	Gene Ontology	description	Class
1.20619	cation transport	Sodium/potassium-transporting ATPase subunit alpha-4 (EC 3.6.3.9) (Sodium pump subunit alpha-4) (Na(+)/K(+) ATPase alpha-4 subunit). [Uniprot/SWISSPROT;Acc:Q13733]	biological process
	GABA-B receptor activity		molecular function
	hydrogen ion homeostasis		biological process
	hydrolase activity		molecular function
	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
	integral to membrane		cellular component
	magnesium ion binding		molecular function
	membrane		cellular component
	metabolic process		biological process
	monovalent inorganic cation transport
	monovalent inorganic cation transporter activity		molecular function
	nucleotide binding
	potassium ion binding
	potassium ion transport		biological process
	proton transport
	sodium ion binding		molecular function
	sodium ion transport		biological process
	sodium:potassium-exchanging ATPase activity		molecular function
	sodium:potassium-exchanging ATPase complex		cellular component
	sperm motility		biological process
	transport
1.20924	3-chloroallyl aldehyde dehydrogenase activity	Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3). [Uniprot/SWISSPROT;Acc:P47895]	molecular function
	alcohol metabolic process		biological process
	aldehyde dehydrogenase [NAD(P)+] activity		molecular function
	cytoplasm		cellular component
	embryonic eye morphogenesis		biological process
	lipid metabolic process
	metabolic process
	nucleus accumbens development
	optic cup morphogenesis involved in camera-type eye development
	oxidoreductase activity		molecular function
	positive regulation of apoptosis		biological process
	retinoic acid metabolic process
1.21384	catalytic activity	Disco-interacting protein 2 homolog C. [Uniprot/SWISSPROT;Acc:Q9Y2E4]	molecular function
	metabolic process		biological process
	nucleus		cellular component
	transcription factor binding		molecular function
1.21871	apoptotic program	Bcl-2-interacting killer (Apoptosis inducer NBK) (BP4) (BIP1). [Uniprot/SWISSPROT;Acc:Q13323]	biological process
	induction of apoptosis
	integral to membrane		cellular component
	membrane
	mitochondrial envelope
	protein binding		molecular function
	regulation of apoptosis		biological process
1.23668	actin binding	Myosin-If (Myosin-Ie). [Uniprot/SWISSPROT;Acc:O00160]	molecular function
	ATP binding
	biological_process		biological process
	calmodulin binding		molecular function
	motor activity
	myosin complex		cellular component

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.