MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Regulation	Ratio	Gene Ontology	description	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1005 to 1054 of 2667 in total

Regulation  : down

Ratio	Gene Ontology	description	Class
3.66058	extracellular matrix binding	olfactomedin-like 2A [RefSeq_peptide;Acc:NP_872293]	molecular function
	latrotoxin receptor activity
	membrane		cellular component
	protein homodimerization activity		molecular function
3.71868	nucleus	Protein pelota homolog. [Uniprot/SWISSPROT;Acc:Q9BRX2]	cellular component
	protein binding		molecular function
	translation		biological process
3.83977	cytoplasm	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac). [Uniprot/SWISSPROT;Acc:Q8WYP5]	cellular component
	DNA binding		molecular function
	multicellular organismal development		biological process
	nuclear matrix		cellular component
	nucleus
	regulation of transcription		biological process
	transcription
	transcription factor activity		molecular function
3.99682	ATP binding	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein). [Uniprot/SWISSPROT;Acc:Q9P232]
	cell adhesion		biological process
	GPI anchor binding		molecular function
	interleukin-1 receptor activity
	membrane		cellular component
	protein amino acid phosphorylation		biological process
	protein binding		molecular function
	vascular endothelial growth factor receptor activity
4.14557	ATP binding	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3). [Uniprot/SWISSPROT;Acc:Q8IV63]
	nucleotide binding
	nucleus		cellular component
	protein amino acid phosphorylation		biological process
	protein kinase activity		molecular function
	protein serine/threonine kinase activity
	transferase activity
4.21401	membrane	Uncharacterized protein C17orf56. [Uniprot/SWISSPROT;Acc:Q96N21]	cellular component
4.40797	alcohol metabolic process	Aldehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.3) (ALDH class 2) (ALDHI) (ALDH-E2). [Uniprot/SWISSPROT;Acc:P05091]	biological process
	aldehyde dehydrogenase (NAD) activity		molecular function
	aldehyde dehydrogenase [NAD(P)+] activity
	carbohydrate metabolic process		biological process
	electron carrier activity		molecular function
	metabolic process		biological process
	mitochondrion		cellular component
	neuropeptide hormone activity		molecular function
	neuropeptide signaling pathway		biological process
	oxidoreductase activity		molecular function
4.4149	DNA binding	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5). [Uniprot/SWISSPROT;Acc:P17861]
	immune response		biological process
	nucleus		cellular component
	protein dimerization activity		molecular function
	regulation of transcription		biological process
	regulation of transcription, DNA-dependent
	sequence-specific DNA binding		molecular function
	transcription		biological process
	transcription factor activity		molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.