MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio	Regulation	description	Class	Gene Ontology	Accession	Minimum Ratio	Gene	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1 to 9 of 9 in total

Class  : biological process
Gene Ontology  : small GTPase mediated signal transduction

Ratio	Regulation	description
1.21657	up	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1). [Uniprot/SWISSPROT;Acc:Q99719]
1.40602		GTP-binding protein SAR1a (COPII-associated small GTPase). [Uniprot/SWISSPROT;Acc:Q9NR31]
1.49923	down	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP). [Uniprot/SWISSPROT;Acc:Q13905]
1.7961	up	RAS-like, family 11, member A [RefSeq_peptide;Acc:NP_996563]
1.89308		Ras-related protein Rab-36. [Uniprot/SWISSPROT;Acc:O95755]
1.95876		Ras-related protein Rab-17. [Uniprot/SWISSPROT;Acc:Q9H0T7]
3.64872		GTP-binding protein Rhes precursor (Ras homolog enriched in striatum) (Tumor endothelial marker 2). [Uniprot/SWISSPROT;Acc:Q96D21]
5.31521		Rho-related BTB domain-containing protein 1. [Uniprot/SWISSPROT;Acc:O94844]
5.53059		rab and DnaJ domain containing [RefSeq_peptide;Acc:NP_057628]

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.