MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Gene Ontology	Regulation	Gene	Accession	Class	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 451 to 500 of 2667 in total

description	Ratio	Gene Ontology	Regulation	Class
Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta). [Uniprot/SWISSPROT;Acc:Q14839]	1.78439	chromatin assembly or disassembly	up	biological process
		chromatin binding		molecular function
		chromatin modification		biological process
		chromosome organization and biogenesis (sensu Eukaryota)
		DNA binding		molecular function
		helicase activity
		hydrolase activity
		intracellular signaling cascade		biological process
		metal ion binding		molecular function
		nucleic acid binding
		nucleotide binding
		nucleus		cellular component
		protein binding		molecular function
		regulation of transcription from RNA polymerase II promoter		biological process
		transcription
		transcription factor binding		molecular function
		zinc ion binding
Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein). [Uniprot/SWISSPROT;Acc:Q8TD26]	1.60746	ATP binding	down
		ATP-dependent helicase activity
		chromatin		cellular component
		chromatin assembly or disassembly		biological process
		chromatin binding		molecular function
		chromatin remodeling		biological process
		DNA binding		molecular function
		helicase activity
		hydrolase activity
		integral to membrane		cellular component
		nervous system development		biological process
		nucleic acid binding		molecular function
		nucleosome		cellular component
		nucleosome assembly		biological process
		nucleotide binding		molecular function
		nucleus		cellular component
		regulation of transcription, DNA-dependent		biological process
		response to antibiotic
		tetracycline transport
		tetracycline:hydrogen antiporter activity		molecular function
		transcription		biological process
Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Uniprot/SWISSPROT;Acc:Q9P2D1]	1.25808	adult heart development	up
		adult walking behavior
		ATP binding		molecular function
		blood vessel development		biological process
		camera-type eye development
		chromatin		cellular component
		chromatin assembly or disassembly		biological process
		chromatin binding		molecular function
		chromatin modification		biological process
		circulation
		DNA binding		molecular function
		embryonic hindlimb morphogenesis		biological process

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.