MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Gene Ontology	Ratio	Accession	Regulation	description	Class	Minimum Ratio	Gene	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1 to 7 of 7 in total

Gene Ontology  : lipid metabolic process
Class  : biological process

Ratio	Regulation	description
1.20924	down	Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3). [Uniprot/SWISSPROT;Acc:P47895]
1.23845		Insulin-induced gene 1 protein (INSIG-1). [Uniprot/SWISSPROT;Acc:O15503]
1.30207		Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein). [Uniprot/SWISSPROT;Acc:Q5SW96]
1.89168		Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10). [Uniprot/SWISSPROT;Acc:O95125]
2.51088		Epididymal-specific lipocalin-12 precursor. [Uniprot/SWISSPROT;Acc:Q6JVE5]
3.31364	up	Diacylglycerol O-acyltransferase 2 (EC 2.3.1.20) (Diglyceride acyltransferase 2). [Uniprot/SWISSPROT;Acc:Q96PD7]
5.19755		Adiponectin receptor protein 1 (Progestin and adipoQ receptor family member I). [Uniprot/SWISSPROT;Acc:Q96A54]

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.