Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes


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Minimum Ratio Gene Ontology Regulation Accession Ratio description Gene Class Maximum Ratio
Results: HTML CSV LaTeX Showing element 1 to 3 of 3 in total
Gene Ontology  : protein serine/threonine phosphatase activity
Class  : molecular function
Regulation
Ratio
description
down 1.72656 protein phosphatase 1, regulatory subunit 15B [RefSeq_peptide;Acc:NP_116222]
up 1.59819 Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2). [Uniprot/SWISSPROT;Acc:O14830]
2.2866 Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (IA). [Uniprot/SWISSPROT;Acc:P35813]

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

- http://analysis.yellowcouch.org/