Scientific

Methylation/Acetylation Patterns


Scaling | Absolute | Relative
Extraction | Transcript | Exon/Intron Alternations | Genomic
Horizontal | H2BK5me1 | H3K27me1 | H3K27me2 | H3K27me3 | H3K36me1 | H3K36me3 | H3K4me1 | H3K4me2 | H3K4me3 | H3K79me1 | H3K79me2 | H3K79me3 | H3K9me1 | H3K9me2 | H3K9me3 | H3R2me1 | H3R2me2 | H4K20me1 | H4K20me3 | H4R3me2
| H2AK5ac | H2BK120ac | H2BK12ac | H2BK20ac | H2BK5ac | H2AK9ac | H3K14ac | H3K18ac | H3K23ac | H3K27ac | H3K36ac | H3K4ac | H3K9ac | H4K12ac | H4K16ac | H4K5ac | H4K8ac | H4K91ac
| CTCF | H2AZ | PolII
Vertical | H2BK5me1 | H3K27me1 | H3K27me2 | H3K27me3 | H3K36me1 | H3K36me3 | H3K4me1 | H3K4me2 | H3K4me3 | H3K79me1 | H3K79me2 | H3K79me3 | H3K9me1 | H3K9me2 | H3K9me3 | H3R2me1 | H3R2me2 | H4K20me1 | H4K20me3 | H4R3me2
| H2AK5ac | H2BK120ac | H2BK12ac | H2BK20ac | H2BK5ac | H2AK9ac | H3K14ac | H3K18ac | H3K23ac | H3K27ac | H3K36ac | H3K4ac | H3K9ac | H4K12ac | H4K16ac | H4K5ac | H4K8ac | H4K91ac
| CTCF | H2AZ | PolII
Maximization Layer | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15


In short, the right image shows the correlation between the signal around the TSS of a paritcular histone modification (horizontal) against the signal around the TSS of a paritcular other histone modification (vertical). The color reflects the correlation strength.

The 'Extraction' parameter describes how the tss is extracted. One can pieces together only the transcribed DNA (exons placed behind each other), one can choose to have an alteration of exons and introns. In this case the iamge will show various bands; or one can choose to have the strict genomic DNA without making a distinction between exons and introns.

A detailed description of the maps shown below can be found at http://werner.yellowcouch.org/Papers/dsapaper/index.html


- http://analysis.yellowcouch.org/