Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description green Gene red Rank Value Type Network Comparison Type Interaction Map Filtered network_comparison
Results: HTML CSV LaTeX Showing element 1 to 50 of 77072 in total
description
green
red
Rank
Value Type
Network Comparison Type
Interaction Map
Filtered
network_comparison
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] 17.0804 16.298 537 Rooted Divided Low confidence 0 1.04801
634 Subtracted 0.7824
18.0183 11.844 53 Divided High confidence 1.5213
69 Subtracted 6.1743
47.2654 63.8686 64 Divided 1 1.35128
67 Subtracted 16.6032
72.6287 71.9496 4914 Divided Low confidence 1.00944
4919 Subtracted 0.6791
201.5 199.383 4130 Ranked Divided 1.01062
4141 Subtracted 2.117
245.247 185.678 18 Divided High confidence 1.32082
54 Subtracted 59.569
851.77 645.504 131 Measured Divided Low confidence 0 1.31954
273 Subtracted 206.266
934.348 334.401 37 Divided High confidence 2.79409
45 Subtracted 599.947
1034.13 101.05 37 Squared Divided 10.2338
131 Subtracted 933.08
1268.51 775.72 146 Divided Low confidence 1.63527
319 Subtracted 492.79
2765.82 4489.19 60 Measured Divided High confidence 1 1.6231
164 Subtracted 1723.37
6768.05 8875.01 245 Squared Divided 1.31131
1962 Subtracted 2106.96
7900.54 7853.62 4909 Measured Low confidence 46.92
4914 Divided 1.00597
13590.3 13205.3 600 Ranked Subtracted 0 385
629 Divided 1.02915
13895.8 15260.6 172 Subtracted High confidence 1364.8
242 Divided 1.09822
41688.5 43628.5 1119 Squared Low confidence 1 1.04654
1423 Subtracted 1940
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943] 76.3375 73.5001 980 Rooted 2.8374
1092 Divided 1.0386
79.1513 74.3557 610 Subtracted High confidence 4.7956
805 Divided 1.0645
181.041 186.741 1038 Ranked 1.03148
1120 Subtracted 5.7
194.038 198.342 1328 Divided Low confidence 1.02218
1408 Subtracted 4.304
8585.64 8255.95 780 Measured 329.69
885 Divided 1.03993
8630.06 7551.8 310 Subtracted High confidence 1078.26
509 Divided 1.14278
39351.7 30807.7 274 Squared Subtracted 8544
295 Divided 1.27733
45736 46617.7 4514 Subtracted Low confidence 881.7
4562 Divided 1.01928
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120] 76.3467 73.5068 977 Rooted Subtracted 2.8399
1084 Divided 1.03863

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/