Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Value Type Gene Rank Interaction Map Network Comparison Type description Filtered green red network_comparison
Results: HTML CSV LaTeX Showing element 551 to 600 of 77072 in total
Value Type  : Measured
Rank
Interaction Map
Network Comparison Type
description
Filtered
green
red
network_comparison
69 Low confidence Subtracted trypsin i precursor (ec 3.4.21.4) (cationic trypsinogen). [swissprot;acc:p07477] 1 3007.85 1983.91 1023.94
zinc finger protein 223. [swissprot;acc:q9uk11] 0 1971.21 2354.34 383.13
70 High confidence Divided amp deaminase 2 (ec 3.5.4.6) (amp deaminase isoform l). [swissprot;acc:q01433] 1 10307.5 6475.5 1.59177
importin alpha-2 subunit (karyopherin alpha-2 subunit) (srp1-alpha) (rag cohort protein 1). [swissprot;acc:p52292] 0 1068 607 1.75947
Subtracted beta-carotene dioxygenase 2; putative b,b-carotene-9',10'-dioxygenase. [refseq;acc:nm_031938] 139 570 431
serine/threonine protein phosphatase 2a, 56 kda regulatory subunit, epsilon isoform (pp2a, b subunit, b' epsilon isoform) (pp2a, b subunit, b56 epsilon isoform) (pp2a, b subunit, pr61 epsilon isoform) (pp2a, b subunit, r5 epsilon isoform). [swissprot;acc:q16537] 1 13995.7 17738.5 3742.8
Low confidence Divided synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296] 0 305.886 167.73 1.82368
y+l amino acid transporter 1 (y(+)l-type amino acid transporter 1) (y+lat-1) (y+lat1) (monocyte amino acid permease 2) (mop-2). [swissprot;acc:q9um01] 1 7848.45 6991.78 1.12253
Subtracted septin 1 (larp) (serologically defined breast cancer antigen ny-br- 24). [swissprot;acc:q8wyj6] 11515.8 10499 1016.8
zinc finger imprinted 3. [swissprot;acc:q96pe6] 0 1971.17 2354.3 383.13
71 High confidence Divided serine/threonine protein phosphatase 2a, 55 kda regulatory subunit b, alpha isoform (pp2a, subunit b, b-alpha isoform) (pp2a, subunit b, b55-alpha isoform) (pp2a, subunit b, pr55-alpha isoform) (pp2a, subunit b, r2-alpha isoform). [swissprot;acc:q00007] 1 2945.26 4556.78 1.54716
ubiquitin protein ligase. [refseq;acc:nm_130466] 0 352.75 620 1.75762
Subtracted serine/threonine protein phosphatase 2a, 56 kda regulatory subunit, alpha isoform (pp2a, b subunit, b' alpha isoform) (pp2a, b subunit, b56 alpha isoform) (pp2a, b subunit, pr61 alpha isoform) (pp2a, b subunit, r5 alpha isoform). [swissprot;acc:q15172] 1 13995.7 17738.5 3742.8
tubby protein homolog. [swissprot;acc:p50607] 0 4228.27 3797.57 430.7
Low confidence Divided cystine/glutamate transporter (amino acid transport system xc-) (xct) (calcium channel blocker resistance protein ccbr1). [swissprot;acc:q9upy5] 1 7848.45 6991.78 1.12253
zona pellucida sperm-binding protein 3 precursor (zona pellucida glycoprotein zp3) (zona pellucida protein c) (sperm receptor) (zp3a/zp3b). [swissprot;acc:p21754] 0 150.001 270.432 1.80287
Subtracted protein cgi-126 (protein hspc155). [swissprot;acc:q9y3c8] 1 6352.4 5339.5 1012.9
zinc finger protein 233. [refseq;acc:nm_181756] 0 1970.95 2354.06 383.11
72 High confidence Divided 60s ribosomal protein l21. [swissprot;acc:p46778] 992.083 572 1.73441
uncharacterized hematopoietic stem/progenitor cells protein mds026. [sptrembl;acc:q9nz48] 1 2945.28 4556.79 1.54715
Subtracted b-raf proto-oncogene serine/threonine-protein kinase (ec 2.7.1.-) (p94) (v-raf murine sarcoma viral oncogene homolog b1). [swissprot;acc:p15056] 13977.7 17710.9 3733.2
rab gdp dissociation inhibitor alpha (rab gdi alpha) (gdi-1) (xap-4) (oligophrenin 2). [swissprot;acc:p31150] 0 1106.88 679.449 427.431
Low confidence Divided b24o18.3 (pom121 membrane glycoprotein (rat homolog)-like 2). [sptrembl;acc:q96kw2] 150.995 271.129 1.79562
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6. [refseq;acc:nm_003983] 1 7848.45 6991.78 1.12253
Subtracted serine/threonine-protein kinase mak (ec 2.7.1.-) (male germ cell- associated kinase). [swissprot;acc:p20794] 10633 9631.47 1001.53
zinc finger protein 334. [swissprot;acc:q9hcz1] 0 1970.91 2354.02 383.11
73 High confidence Divided protein phosphatase inhibitor 2 (ipp-2). [swissprot;acc:p41236] 37.693 65.2968 1.73233
serine/threonine protein phosphatase 2a, 55 kda regulatory subunit b, beta isoform (pp2a, subunit b, b-beta isoform) (pp2a, subunit b, b55- beta isoform) (pp2a, subunit b, pr55-beta isoform) (pp2a, subunit b, r2-beta isoform). [swissprot;acc:q00005] 1 2945.38 4556.83 1.54711
Subtracted sal-like protein 4 (zinc finger protein sall4). [swissprot;acc:q9ujq4] 0 2389.69 1965.47 424.22
serine/threonine protein phosphatase pp1-gamma catalytic subunit (ec 3.1.3.16) (pp-1g). [swissprot;acc:p36873] 1 18560.4 22268.8 3708.4
Low confidence Divided eukaryotic translation initiation factor 4b (eif-4b). [swissprot;acc:p23588] 7848.45 6991.78 1.12253
soluble liver antigen/liver pancreas antigen. [refseq;acc:nm_153825] 0 385.626 688.436 1.78524
Subtracted intestinal cell kinase isoform a; mak-related kinase; serine/threonine protein kinase. [refseq;acc:nm_014920] 1 10621.3 9623.55 997.75
krab zinc finger protein hzf26 (fragment). [sptrembl;acc:q9bze6] 0 1970.8 2353.9 383.1
74 High confidence Divided bone morphogenetic protein 8 precursor (bmp-8) (osteogenic protein 2) (op-2). [swissprot;acc:p34820] 859.34 501.151 1.71473
serine/threonine protein phosphatase 2a, 55 kda regulatory subunit b, gamma isoform (pp2a, subunit b, b-gamma isoform) (pp2a, subunit b, b55-gamma isoform) (pp2a, subunit b, pr55-gamma isoform) (pp2a, subunit b, r2-gamma isoform) (imypno1). [swissprot;acc:q9y2t4] 1 2945.8 4556.99 1.54694
Subtracted glycogenin-2 (ec 2.4.1.186) (gn-2) (gn2). [swissprot;acc:o15488] 0 14688.8 14267.5 421.3
homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017] 1 24136.4 20446.1 3690.3
Low confidence Divided arf gtpase-activating protein. [refseq;acc:nm_133446] 0 37 66 1.78378
b(0,+)-type amino acid transporter 1 (b(0,+)at) (glycoprotein- associated amino acid transporter b0,+at1). [swissprot;acc:p82251] 1 7848.45 6991.78 1.12253
Subtracted melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801] 10318.5 11285.3 966.8
zinc finger protein 195. [swissprot;acc:o14628] 0 1970.76 2353.86 383.1
75 High confidence Divided nadh-ubiquinone oxidoreductase 18 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-18 kda) (ci-18 kda) (complex i- aqdq) (ci-aqdq). [swissprot;acc:o43181] 1 2907.43 1920.75 1.5137
oligosaccharyl transferase stt3 subunit homolog (b5) (integral membrane protein 1) (tmc). [swissprot;acc:p46977] 0 925.298 1586.07 1.71412
Subtracted 60s ribosomal protein l21. [swissprot;acc:p46778] 992.083 572 420.083
homeobox protein hox-b4 (hox-2f) (hox-2.6). [swissprot;acc:p17483] 1 24136.4 20446.1 3690.3
Low confidence Divided septin 7 (cdc10 protein homolog). [swissprot;acc:q16181] 12942.3 11616 1.11418
up-regulated in liver cancer 1; similar to development- and differentiation-enhancing factor 2. [refseq;acc:nm_017707] 0 37 66 1.78378
Subtracted hepatocellular carcinoma-associated protein hca3. [refseq;acc:nm_138703] 1 10318.5 11285.3 966.8
zinc finger protein 230 (zinc finger protein fdzf2). [swissprot;acc:q9uie0] 0 1970.7 2353.79 383.09

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/